This course is provided by the NYCUCollege of Life ciences.

This course is " Informatics for translational medicine ".

In 2004, the president of the U.S. National Academy of Sciences proposed the concept of "translational medicine," hoping to transform the results of genomic research into clinical applications through the interaction between basic and clinical medicine. A few years later, with the development of next generation sequencing (NGS) technology, a large amount of high throughput analysis data and big data has been accumulated. By using massive amounts of data for data mining, "precision medicine" is also moving towards personalized medicine and preventive medicine.

In the process of converting the results of genomic research into clinical applications, it is necessary to find the correlation between clinical and high-throughput data. This involves ethical, legal and social issues (ELSI) such as protecting personal privacy.

This course will use applied examples to explain to students how to interpret the pathogenic mechanism at the molecular level, then associate the pathogenic mechanism with clinical application, and make it a consensus for treatment through experiments.

Reference Data：

衛生福利部疾病管制署，http://www.cdc.gov.tw/  

衛生福利部資料科學中心，https://dep.mohw.gov.tw/DOS/cp-5119-59201-113.html

中央研究院臺灣人體生物資料庫，https://www.twbiobank.org.tw/new_web/index.php 

中央研究院台灣精準醫療計畫，https://tpmi.ibms.sinica.edu.tw

美國國家衛生研究院，https://www.nih.gov/

美國國家癌症研究所，https://portal.gdc.cancer.gov/ 

美國國家生物技術資訊中心， https://www.ncbi.nlm.nih.gov/ 

其他國內外相關來源 :

2004，美國生物醫學研究 : 基礎科學、轉譯科學和臨床科學。https://pubmed.ncbi.nlm.nih.gov/16174693/

2011，美國國家科學院 : 邁向精準醫療。https://pubmed.ncbi.nlm.nih.gov/22536618/

2012，楊永正，「結合醫療、生活與基因資訊，迎向智慧醫療的新世代。IBM 2012智慧醫療研討會。Aug. 24, 2012。https://www.digitimes.com.tw/tech/dt/n/shwnws.asp?id=0000300861_2G67S91A706Q7O09H0D9I

2014，衛生福利部國民健康資訊建設計畫(National Health Informatics Project, NHIP)」。https://hdsr.ym.edu.tw/files/11-1274-1530.php?Lang=zh-tw

2015，美國國家衛生研究院，精準醫學計畫的近程與長程目標。https://www.nih.gov/sites/default/files/research-training/initiatives/pmi/pmi-working-group-report-20150917-2.pdf

2016，世界醫師會大會「台北宣言：健康資料庫與生物資料庫之倫理考量」。https://hualien.tzuchi.com.tw/rec/images/stories/files/regulation/2016_Declaration_of_Taipei-_Chinese.pdf