This course is provided by the NYCU College of Medicine.

Pharmacokinetics basically explores the journey of drug absorption, distribution, metabolism, and excretion in the body, how drugs enter the systemic circulation, how the body's enzymes metabolize drugs, and how drugs pass through biological barriers. Compared to pharmacodynamics, which is the effect of drugs on the body, pharmacokinetics is the effect of the body on the drugs.
This course will also introduce the basic theories of zero-order and first-order kinetics and the compartment theory of pharmacokinetics. Due to the epidemic of COVID-19, Pfizer’s experimental pharmacokinetic data, including the dose-dependent of Paxlovid (a combination antiviral medication of nirmatrelvir + ritonavir used to treat COVID-19), whether food affects the pharmacokinetics of Paxlovid, whether racial differences affect pharmacokinetics, etc., were also discussed in class.

Textbook：
Goodman & Gilman's: The Pharmacological Basis of Therapeutics, 14th Edition, 2023.
Section I: General Principles

Laurence L. Brunton, Björn C. Knollmann

Applied Biopharmaceutics & Pharmacokinetics, 7e, 2016
Leon Shargel, Andrew B.C. Yu

ical Microbiology, 9th Edition by  Murray,  Rosenthal and  Pfaller.

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